Ingredients Each capsule Pax+/ Pax + forte contains:

• Lemon Balm (Melissa officinalis L. )                                 50 mg
• Lavender powder (Lavandula angustifolia miller)           50 mg
• Valerian root powder (Valeriana officinalis) — 50 mg (Pax + forte) or Poppy petals — rhoeas (Papaver rhoeas L.) — 50 mg (Pax +)
• Vitamin B1                                                                       1.15 mg
• Vitamin B2                                                                       1.62 mg
• Vitamin B5                                                                        6.02 mg
• Vitamin B6                                                                        1.63 mg
• Vitamin B9                                                                         0.2 mg
• Vitamin B12                                                                       1.01 µg
• Vitamin PP                                                                         17.82 mg
• Vitamin H (Biotin)                                                               0.12 mg
• Calcium hydrophosphate (including calcium 24.75 mg)      116 mg
• Magnesium carbonate (ncluding magnesium 26.02 mg)    100 mg

Lemon Balm (Melissa officinalis L. )

• The plant has sedative, antispasmodic, hypotensive, analgesic, antimicrobial and antihistamine effects.
• Concentrates selenium.
• Melissa is effective in :
  • hypertension
  • tachycardia
  • asthma
  • depression
  • nervous stress
  • migraines
  • insomnia
  • painful menstruation
  • means of normalizing the digestive processes

Lavender powder (Lavandula angustifolia miller)

• English lavender (lavandula angustifolia miller) contains volatile oils that reduce anxiety, tension, agitation, and nervousness.
• Lavender has a sedative, antispasmodic, diuretic and antimicrobial action.
• It is effective in:
  • hypertension
  • neurasthenia
  • migraine headaches
  • tachycardia
  • mild sedative
• It is used to relieve nervous tension and anxiety, promotes over all relaxation, normalize digestion.

Valerian root powder (Valeriana officinalis)

• Valerian has a sedative, tranquilizing, antispasmodic, anticonvulsant activity, has a positive regulatory effect on the heart, including the mechanisms of automaticity and its conducting system, improves coronary circulation and helps reduce blood pressure.
• It has a hypnotic effect, improves sleep quality, including patients suffering from insomnia and excitement, does not cause morning drowsiness feeling.
• Stimulates the secretion and secretory function of the stomach and pancreas.
• It is used for :
  • nervous agitation
  • insomnia
  • migraine
  • neurasthenia
  • diseases of the cardiovascular system
  • leading to spasms of the coronary arteries, and tachycardia
  • menopausal disorders
  • bronchial asthma
  • neurodermatitis
  • thyrotoxicosis
• Used in conjunction with other sedatives to treat liver diseases, spastic conditions of the gastrointestinal tract.

Poppy petals — rhoeas (Papaver rhoeas L.)

• Poppy petals contain alkaloids, saponins, bioflavonoids, etc.
• It is used as a sedative, is used for normalization of sleep and heart.
• There are 2 types of plants: the field poppy and the poppy cultivated by man. Its traditional uses are:
  • it treats cough and insomnia.
  • with the tea made of poppy leaves are treated throat aches through throat wash.
  • tea made of poppy petals is used against hemorrhage.
• In the old times physicians used morphine made from poppy, to put patients to sleep so they could perform the necessary chirurgical interventions. Today morphine is used under medical control to calm the patient's pain.

• Thiamine works with the other B vitamins to change protein, carbohydrate, and fat to energy. It is especially vital for changing carbohydrates to energy. It is a key factor in the healthy functioning of all the body’s cells, especially the nerves.
• Vitamin B1 helps the body cells convert carbohydrates into energy. It is also essential for the functioning of the heart, muscles, and nervous system. As a coenzyme, thiamin plays a key role in energy production, conversion of glucose to fat. Every cell of the body requires vitamin B1 to form the fuel the body runs on — ATP. Nerve cells require vitamin B1 in order to function normally.
• Thiamin is needed for the metabolism of carbohydrates, fat, and protein. It is especially involved in carbohydrate metabolism in the brain.
• Thiamin may be used to support nerve health, and minimize numbness and tingling, helping to protect against this condition.
• Thiamine aids the nervous system and is essential for the functioning of important enzymes. These enzymes have vital roles in the processes that make energy available in the body. Thiamine is essential for the transmission of certain types of nerve signal between the brain and the spinal cord.
• Depression, poor memory, muscle weakness and stiffness, nerve tingling, burning sensation and numbness, tiredness, headache, loss of appetite and nausea are some of the symptoms and signs of its deficiency.

Vitamin B2

• Riboflavin (vitamin B2) plays a crucial role in certain metabolic reactions, particularly the conversion of carbohydrates into sugar, which is «burned» to produce energy.
• Riboflavin is essential for tissue respiration and the generation of energy from the carbohydrates, acids and fats. It is important for body growth and red blood cell production and helps in releasing energy from carbohydrates.
• Vitamin B2 helps prevent and is used to treat migraine headaches, cataracts, rheumatoid arthritis, and a number of skin disorders such as acne (acne rosacea), dermatitis, and eczema.
• Vital to maintaining a proper metabolism, riboflavin also helps to shore up the immune system by reinforcing antibody reserves, the body’s first line of defense against infection.
• Along with iron, riboflavin is essential for producing the red blood cells that carry oxygen throughout the body.
• The body uses extra riboflavin to keep tissue in good repair and speed healing of wounds, burns and other injuries.
• Riboflavin protects the nervous system. It may therefore have a role to play in treating nervous system conditions such as numbness and tingling, Alzheimer’s disease, epilepsy, multiple sclerosis, and even anxiety, stress, and fatigue.
• Riboflavin is vital for normal reproduction, growth, repair and development of body tissues including the skin, hair, nails, connective tissue and immune system.
• Riboflavin is important for normal vision and prevention of cataracts.
• Riboflavin’s ability to improve the skin’s secretion of mucus may aid in clearing up skin pustules associated with rosacea.

Vitamin B5

• Vitamin B5 is essential for human growth
• Vitamin B5 helps metabolize nutrients, manufacture antibodies and produce vitamin D
• It also stimulates the healing of wounds
• Pantothenic acid is involved in a number of biological reactions, including the production of energy, the catabolism of fatty acids and amino acids, the synthesis of fatty acids, lipids, cholesterol and steroid hormones
• Vitamin B5 is critical to the manufacture of red blood cells as well as sex and stress-related hormones produced in the adrenal glands (small glands that sit atop of the kidneys)
• Supplements are sometimes used to treat symptoms of allergy and a wide range of skin conditions
• Vitamin B5 is important in maintaining a healthy digestive tract and it helps the body use other vitamins more effectively
• Pantothenic acid may help to manage stress from psychological strain, migraines, chronic fatigue syndrome, and smoking and alcohol cessation

Vitamin B6

• Vitamin B6 supports more vital bodily functions than any other vitamin.
• It is vital in the metabolism of amino acids in the intestines. It allows the amino acids to be synthesized, broken down and absorbed.
• The forming of histamine, serotonin, dopamine and adrenaline are dependent on vitamin B6.
• Vitamin B6 helps to maintain healthy immune system functions, to protect the heart from cholesterol deposits, and to prevent kidney stone formation.
• Vitamin B6 is indicated for the treatment of anemia, neurologic disturbances, seborrhoeic dermatitis, and cheilosis.
• In combination with folic acid and vitamin B12, vitamin B6 lowers homocysteine levels which is an amino acid linked to heart disease and stroke, and possibly other diseases as well, such as osteoporosis, and Alzheimer’s disease.
• Pyridoxine is required for the balancing of hormonal changes in women as well as assisting the immune system and the growth of new cells.

Vitamin B9(Folic acid)

• Folic acid plays an essential role in human growth and development, in particular cell division and DNA synthesis.
• Folic acid is involved in every bodily function that requires cell division.
• Folic acid works along with vitamin B12 and vitamin C to help the body digest and utilize proteins and to synthesize new proteins when they are needed.
• Folic acid is important for any stage of human life which involves growth such as pregnancy, lactation and early growth because of the role the folate plays in DNA, RNA and protein production.
• Folic acid is indicated for the prevention of some birth defects and appears to confer significant protection against cardiovascular disease and some forms of cancer.
• Folic acid may be used in the treatment of disorders associated with folic acid deficiency and may also be part of the recommended treatment for certain menstrual problems and leg ulcers.
• Folic acid also helps with tissue growth and cell function.
• It helps to increase appetite when needed and stimulates the formation of digestive acids.
• Pregnant women have an increased need for folic acid, both for themselves and their child. Folic acid also is crucial to support the rapid growth of the placenta and fetus. Taken as part of a B-complex vitamin that contains biotin and vitamin B12, folic acid can strengthen the reproductive system in women having trouble conceiving. Without adequate amounts of folic acid, cell division could be impaired, possibly leading to poor growth in the fetus or placenta. Adequate intake of folic acid is vital for the prevention of several types of birth defects, particularly neural tube defects.
• Folic acid appears to regulate the body’s production and use of homocysteine. High levels of a substance called homocysteine in the blood is considered to be a risk factor for heart disease. People who are at high risk of strokes and heart disease may greatly benefit by taking folic acid supplements.
• High levels of homocysteine have also been found to contribute to problems with osteoporosis. Folic acid, together with vitamins B6 and B12, helps break down homocysteine, and may help reverse the problems associated with elevated levels.
• Folate status is associated with colorectal, lung, esophageal, brain, cervical and breast cancers.
• Folate is involved in the synthesis, repair, and functioning of DNA, our genetic map, and a deficiency of folate may result in damage to DNA that may lead to cancer.
• Folate is important for cells and tissues that rapidly divide.
• Because folic acid is often deficient in those who are depressed, a supplement may help. Vitamin B9 (folate) may be associated with depression more than any other nutrient, and may play a role in the high incidence of depression in the elderly.

Vitamin B12

• Vitamin B12′s main functions are in the formation of red blood cells and the maintenence of a healthy nervous system.
• Vitamin B12 is an especially important vitamin for maintaining healthy nerve cells and it aids in the production of DNA and RNA, the body’s genetic material. Cyanocobalamin works to promote normal growth and development, helps with certain types of nerve damage, and treats pernicious anemia.
• Nerves are surrounded by an insulating fatty sheath comprised of a complex protein called myelin. Vitamin B12 helps maintain the myelin sheath that insulates nerve fibres from each other. People with vitamin B12 deficiency show irregular destruction of the myelin sheaths, which eventually causes paralysis and death.
• Vitamin B12 is essential for the proper production of blood platelets and red and white blood cells, the manufacture of vital substances needed for cell function, and the metabolism of nutrients necessary for cell growth.
• It participates in a variety of cellular reactions to release energy from carbohydrates, fats and protein.

Vitamin PP

• Vitamin PP(niacin) is a key in releasing energy from carbohydrates, processing alcohol, forming fats, and producing sex hormones.
• Niacin helps  to prevent recurrent heart attack.
• Niacin helps regulate cholesterol levels.
• Vitamin PP is used in diseases of :
  • the heart and liver
  • stomach ulcers and 12 duodenal ulcer
  • enterocolitis
  • weak healing ulcers and wounds
  • infectious diseases
• Vitamin РР in combination with vitamin E is used in the treatment of mild forms of diabetes.
• Its deficiency leads to development of dermatitis and symptoms indicating a violation of the nervous system and gastrointestinal tract: nausea, loss of appetite, discomfort in the stomach, severe weakness, memory impairment.

Vitamin H (Biotin)

• The primary role of biotin is in the metabolism of fats, proteins and carbohydrates.
• Biotin helps in the synthesis of fatty acids, in energy metabolism, and in the synthesis of amino acids and glucose.
• Vitamin H plays a special role in enabling the body to use blood sugar (glucose), a major source of energy for body fluids.
• Biotin supplements may improve thin, splitting, or brittle toe and fingernails as well as hair health.
• Biotin has also been used to combat alopecia (partial or complete loss of hair) in both children and adults.
• Biotin has also been used to combat premature graying of hair.
• Biotin supplements are sometimes given to help reduce blood sugar in diabetic patients. People with type 2 diabetes often have low levels of biotin.
• Biotin has been used for people in weight loss programs to help them metabolize fat more efficiently.

Calcium

• Calcium are important for the proper formation of bones  and muscles. To activate the calcium in bone tissue requires vitamin D, phosphate, magnesium, zinc, manganese, ascorbic acid, and other factors. 
• Calcium reduces the manifestations of allergic reactions, pain syndromes and inflammatory processes. 
• It is a factor in blood clotting. Lowers blood cholesterol. 
• Participates in the formation of an immune response. Inadequate intake of calcium in the body increases the excretion of calcium from the bones into the bloodstream, causing bone demineralization and osteoporosis.
• Significantly increases the need for it in pregnant and lactating women. 
• Apply for:
  • the prevention of osteoporosis
  • regulation of the functioning of the CNS
  • the lack of parathyroid function
  • allergic diseases (serum sickness, urticaria, angioedema, hay fever)
  • to reduce vascular permeability (hemorrhagic vasculitis, the phenomenon of radiation sickness, and exudative inflammatory processes)
  • with skin diseases (eczema, psoriasis)
  • chronic hepatitis
  • toxic liver damage
  • as a styptic for bleeding
  • as an antidote to poisoning by salts of oxalic acid and fluoride
  • Studies have shown that calcium, particularly in combination with vitamin D, may help prevent bone loss associated with menopause
  • It may also help prevent bone loss in older men

Magnesium

• According to the US National Institute of Health, magnesium is need for more than 300 biochemical processes in the body.  It helps maintain normal muscle and nerve function, keeps heart rhythm steady, supports a healthy immune system, and keeps bones strong.
• Magnesium also helps regulate blood sugar levels, promotes normal blood pressure, and is known to be involved in energy metabolism and protein synthesis.
• There is increased recognition of the role of magnesium in preventing and managing disorders such as hypertension, cardiovascular disease, and diabetes.
• Magnesium has a cardioprotective effect, providing a beneficial effect on heart rhythm disturbances, coronary heart disease, myocardial infarction, improving myocardial oxygen supply. 
• At the same time, magnesium exhibits vasodilator effect and helps reduce blood pressure. 
• Magnesium is an anti-stress macro-elements, has a normalizing effect on the nervous system and its higher parts (especially in combination with vitamin B6) with nervous tension, depression, neurosis.
• Magnesium in diabetes prevents cardiovascular complications and, in combination with zinc, chromium, selenium improves the function of beta cells of the pancreas. 
• In diseases of the respiratory system enhances the removal of the bronchi and bronchospasm. In both cases, magnesium is an important factor in therapy (in combination with fixed assets).
• Magnesium has a positive impact on the reproductive system. 
• In pregnant women, magnesium deficiency prevents the development of the fruit (along with folic and pantothenic acid), the development of gestosis, premature births and miscarriages. 
• At the time of menopause in women reduces the negative manifestations of this condition.